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IWR-1 endo

Overview
Catalog # bs-83086c-5-mg
Product Name IWR-1 endo
Specifications
Storage Buffer Beige solid
Storage Condition -20°C
Target
Product Information A potent inhibitor of Wnt signaling (IC50=180 nM).1 Inhibits zebrafish tailfin regeneration (0.5 mM).2 Acts via inhibition of tankyrase and attenuates Wnt/b-catenin signaling in cancer stem-like cells.3 Promotes self-renewal and maintains pluripotency of human embryonic stem cells.4 Promotes differentiation of pluripotent stem cells into cardiomyocytes.5
Description CAS Number: 1127442-82-3

Chemical Name: 4-(1,3,3a,4,7,7a-Hexahydro-1,3-dioxo-4,7-methano-2H-isoindol-2-yl)-N-8-quinolinyl-benzamide

Molecular weight: 409.44

Formula: C25H19N3O2

Solubility: DMSO (10 mg/ml)

Physical Properties: Off white or yellow solid

Purity: 98% by TLC/HPLC NMR (Conforms)