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DEK (1C7) Monoclonal Antibody

Applications

  • WB
  • IF(ICC)

Reactivity

  • Human
Overview
Catalog # bsm-54339R
Product Name DEK (1C7) Monoclonal Antibody
Applications WB, IF(ICC)
Reactivity Human
Specifications
Conjugation Unconjugated
Host Rabbit
Source Recombinant protein corresponding to C-terminal human DEK.
Clonality Monoclonal
Clone # 1C7
Isotype IgG
Concentration 1ug/ul
Purification Purified by Protein A.
Storage Buffer Aqueous buffered solution containing 1xTBS (pH7.4), 1%BSA, 40%Glycerol and 0.05% Sodium Azide.
Storage Condition Store at 4C for up to 2 weeks. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
Target
Gene ID 7913
Swiss Prot P35659
Subcellular location Nucleus
Synonyms Protein DEK; DEK; DEK proto-oncogene; D6S231E
Background DEK has one SAP domain. DEK binds to cruciform and superhelical DNA and induces positive supercoils into closed circular DNA, and is also involved in splice site selection during mRNA processing. Chromosomal aberrations involving this region, increased expression of this gene, and the presence of antibodies against this protein are all associated with various diseases. Two transcript variants encoding different isoforms have been found for this gene.
Application Dilution
WB 1:300-5000
IF(ICC) 1:50-200