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SNRPA (2A1) Monoclonal Antibody

Applications

  • WB
  • IHC-P
  • IF(ICC)
  • IP
  • IHC

Reactivity

  • Human
  • Mouse
  • Rat
Overview
Catalog # bsm-54338R
Product Name SNRPA (2A1) Monoclonal Antibody
Applications WB, IHC-P, IF(ICC), IP, IHC
Reactivity Human, Mouse, Rat
Specifications
Conjugation Unconjugated
Host Rabbit
Source Recombinant protein corresponding to N-terminal human U1A.
Clonality Monoclonal
Clone # 2A1
Isotype IgG
Concentration 1ug/ul
Purification Purified by Protein A.
Storage Buffer Aqueous buffered solution containing 1xTBS (pH7.4), 1%BSA, 40%Glycerol and 0.05% Sodium Azide.
Storage Condition Store at 4C for up to 2 weeks. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
Target
Gene ID 6626
Swiss Prot P09012
Subcellular location Nucleus
Synonyms U1 small nuclear ribonucleoprotein A; U1 snRNP A; U1-A; U1A; SNRPA
Background Component of the spliceosomal U1 snRNP, which is essential for recognition of the pre-mRNA 5' splice-site and the subsequent assembly of the spliceosome. U1 snRNP is the first snRNP to interact with pre-mRNA. This interaction is required for the subsequent binding of U2 snRNP and the U4/U6/U5 tri-snRNP. SNRPA binds stem loop II of U1 snRNA. In a snRNP-free form (SF-A) may be involved in coupled pre-mRNA splicing and polyadenylation process. May bind preferentially to the 5'-UGCAC-3' motif on RNAs.
Application Dilution
WB 1:300-5000
IHC-P 1:200-400
IF(ICC) 1:50-200
IP 1-2ug
IHC