AM-580

Overview
Catalog #	bs-83129c-5-mg
Product Name	AM-580
Specifications
Storage Buffer	Yellow solid
Storage Condition	-20°C
Target
Product Information	Retinoic acid analog acting as a RARα agonist (Kd = 8 nM).1 Induces or blocks differentiation depending on cell type and environment.2,3 In combination with CHIR-99021 it induces differentiation of human induced pluripotent stem cells (iPSCs) into intermediate mesoderm (80% induction rate in 5 days) capable of forming kidney structures.4 AM-580 exhibits anti-angiogenic activity in vivo, and induces differentiation of acute promyelocytic leukemia cells.5,6
Description	CAS Number: 102121-60-8 Chemical Name: 4-[(5,6,7,8-Tetrahydro-5,5,8,8-tetramethyl-2-naphthalenyl)carboxamido]benzoic acid Molecular weight: 351.45 Formula: C22H25NO3 Solubility: DMSO (35 mg/ml) or ethanol (18 mg/ml) Physical Properties: Off-white solid Purity: >98% by HPLC NMR (Conforms)