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Hsp60 Antibody

Applications

  • WB
  • IHC
  • ICC

Reactivity

  • Human
  • Mouse
  • Rat

Predicted Reactivity

  • Dog
  • Bovine
  • Sheep
  • Horse
  • Cat
  • Rabbit
  • Guinea Pig
  • Goat
  • Zebrafish
  • Hamster
  • Non-Human Primate
Overview
Catalog # bsm-70131M
Product Name Hsp60 Antibody
Applications WB, IHC, ICC
Specificity Specific for endogenous levels of the ~ 60 kDa HSP60 protein.
Reactivity Human, Mouse, Rat
Predicted Reactivity Dog, Bovine, Sheep, Horse, Cat, Rabbit, Guinea Pig, Goat, Zebrafish, Hamster, Non-Human Primate
Specifications
Conjugation Unconjugated
Host Mouse
Source Recombinant full length human HSP60 protein.
Clonality Monoclonal
Clone # 1C7
Isotype IgG1
Concentration Lot Dependent
Purification Purified by Protein G.
Storage Buffer PBS + 50% glycerol and 5 mM NaN3
Storage Condition Storage at -20°C is recommended, as aliquots may be taken without freeze/thawing due to presence of 50% glycerol. Stable for at least 1 year at -20°C.
Target
Gene ID 3329
Swiss Prot P10809
Synonyms 60 kDa chaperonin antibody, 60 kDa heat shock protein, mitochondrial antibody, CH60_HUMAN antibody, Chaperonin 60 antibody, Chaperonin, 60-KD antibody, CPN60 antibody, fa04a05 antibody, GROEL antibody, heat shock 60kDa protein 1 (chaperonin) antibody, Heat shock protein 1 (chaperonin) antibody, Heat shock protein 60 antibody, Heat shock protein 65 antibody, heat shock protein family D (Hsp60) member 1 antibody, HLD4 antibody, Hsp 60 antibody, HSP 65 antibody, HSP-60 antibody, HSP60 antibody, HSP65 antibody, HSPD1 antibody, HuCHA60 antibody, Mitochondrial matrix protein P1 antibody, P60 lymphocyte protein antibody, short heat shock protein 60 Hsp60s1 antibody, SPG13 antibody
Background HSP60 is a member of the heat shock protein family which is thought to play a key role in mitochondrial protein transport and proper refolding of proteins imported from the cytoplasm into the mitochondrial matrix (Koll et al., 1992). More recently, HSP60 has been implicated in the pathogenesis of cardiovascular disease (Rizzo et al., 2011).
Application Dilution
WB 1:300-5000
IHC
ICC 1:100-500