| Overview |
| bsm-70091M |
| FOX1 Antibody |
| WB, IHC, ICC |
| Specific for endogenous levels of the ~46/48 kD FOX1 protein doublet. |
| Human, Mouse, Rat, Bovine |
| Specifications |
| Unconjugated |
| Mouse |
| Recombinant protein taken from the N-terminus of human FOX1 expressed in and purified from E. Coli. |
| Monoclonal |
| 1G10 |
| IgG1 |
| Lot Dependent |
| Purified by Protein G. |
| PBS + 10 mM NaN3. |
| Recommended that the undiluted antibody be aliquoted into smaller working volumes (10-30 uL/vial depending on usage) upon arrival and stored long term at -20° C or -80° C, while keeping a working aliquot stored at 4° C for short term. Avoid freeze/thaw cycles. Stable for at least 1 year. |
| Target |
| 54715 |
| Q9NWB1 |
| 2BP1 antibody, A2 BP1 antibody, A2BP 1 antibody, A2BP antibody, A2BP1 antibody, Ataxin 2 binding protein 1 antibody, Ataxin-2-binding protein 1 antibody, Ataxin2 binding protein 1 antibody, FOX1 antibody, Fox-1 homolog A antibody, fox-1-like RNA-binding protein 1 antibody, Hexaribonucleotide binding protein 1 antibody, Hexaribonucleotide-binding protein 1 antibody, HRNBP 1 antibody, HRNBP1 antibody, RBFOX1 antibody, RFOX1_HUMAN antibody, RNA binding protein fox-1 homolog 1 antibody, RNA binding protein fox-1 homolog 1 C. elegans, homolog of 1 antibody, RNA binding protein fox-1 homolog (C. elegans) 1 antibody |
| FOX1, also known as ataxin-2 binding protein 1 (A2BP1), is a neuron specific RNA-binding protein that has been shown to regulate a wide range of alternative splicing events implicated in neuronal development and maturation including transcription factors and synaptic proteins (Fogel et al., 2012). Defects in FOX1 have also been associated with autism (Martin et al., 2007), attention-deficit hyperactivity disorder (Elia et al., 2010) and schizophrenia (Xu et al., 2008). |
| Application Dilution |
| WB |
1:300-5000 |
| IHC |
|
| ICC |
1:100-500 |
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