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UBE2C Polyclonal Antibody

Applications

  • WB
  • IP
  • IHC
  • IF

Reactivity

  • Human
Overview
Catalog # bs-55218R
Product Name UBE2C Polyclonal Antibody
Applications WB, IP, IHC, IF
Reactivity Human
Specifications
Conjugation Unconjugated
Host Rabbit
Source Recombinant fusion protein containing a sequence corresponding to amino acids 1-179 of human UBE2C (NP_008950.1).
Clonality Polyclonal
Isotype IgG
Concentration 1ug/ul
Purification Purified by Protein A.
Storage Buffer 0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Storage Condition Store at -20°C for 12 months.
Target
Gene ID 11065
Swiss Prot O00762
Subcellular location Cytoplasm, Nucleus, Cell membrane
Synonyms UBE2C;UBCH10;dJ447F3.2
Background The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, ubiquitin-conjugating enzymes, and ubiquitin-protein ligases. This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. The encoded protein is required for the destruction of mitotic cyclins and for cell cycle progression, and may be involved in cancer progression. Multiple transcript variants encoding different isoforms have been found for this gene. Pseudogenes of this gene have been defined on chromosomes 4, 14, 15, 18, and 19.
Application Dilution
WB 1:300-5000
IP 1-2ug
IHC
IF