SR-717
| Overview | |
| Catalog # | bs-83048c-10-mg |
| Product Name | SR-717 |
| Specifications | |
| Storage Buffer | White solid |
| Storage Condition | -20°C |
| Target | |
| Product Information | Cell permeable and exceptionally selective STING agonist (IC50 = 7.8 µM). It displayed robust antitumor activity in B16.F10 melanoma and MC38 colorectal adenocarcinoma mouse models. SR-717 promoted the activation of CD8+ T, natural killer, and dendritic cells as well as promoting antigen cross-priming. It was able to induce PD-L1 expression in THP1 cells and in primary human PBMC’s. |
| Description | CAS Number: 2375421-09-1 Chemical Name: Lithium 2-(6-(1H-Imidazol-1-yl)pyridazine-3-carboxamido)-4,5-difluorobenzoate Molecular weight: 381.27 Formula: C15H8F2N5O3·Li Solubility: DMSO (>25 mg/ml) Physical Properties: Off-white solid Purity: >98% by HPLC NMR (Conforms) |
Powered by Bioz