LDN-192960 HCl
| Overview | |
| Catalog # | bs-83043c-5-mg |
| Product Name | LDN-192960 HCl |
| Specifications | |
| Storage Buffer | Yellow solid |
| Storage Condition | -20°C |
| Target | |
| Product Information | LDN-192960 is a potent inhibitor of Haspin (IC50 = 10 nM), DYRK2 (IC50 = 2 nM), and DYRK3 (IC50 = 19 nM).1,2 It induced cytotoxicity and growth inhibition in multiple myeloma and triple negative breast cancer cells and triple negative breast cancer mouse allo/xenografts via partial inhibition of 26S proteasome activity.3 |
| Description | CAS Number: 184582-62-5 Chemical Name: 3-(2,7-Dimethoxyacridin-9-yl)sulfanylpropan-1-amine dihydrochloride Molecular weight: 401.35 Formula: C18H20N2O2S·2HCl Solubility: DMSO (>25 mg/ml) Water (2 mg/ml) Physical Properties: Yellow solid Purity: >98% by HPLC NMR (Conforms) |
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