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Linsitinib

Overview
Catalog # bs-83031c-10-mg
Product Name Linsitinib
Specifications
Storage Buffer Off-white solid
Storage Condition -20°C
Target
Product Information Linsitinib is a potent and selective dual inhibitor of insulin-like growth factor 1 (IGF-1R) kinase and insulin receptor (InsR) kinase (IC50’s = 35 and 75 nM respectively).1 It has been investigated as a chemotherapeutic in combination with other drugs for various cancers.2-6
Description CAS Number: 867160-71-2

Chemical Name: 3-[8-Amino-1-(2-phenyl-7-quinolyl)imidazo[1,5-a]pyrazin-3-yl]-1-methyl-cyclobutanol

Molecular weight: 421.49

Formula: C26H23N5O

Solubility: DMSO (30 mg/ml)

Physical Properties: Yellow solid

Purity: 98% by HPLC NMR (Conforms)