Linsitinib

Overview
Catalog #	bs-83031c-10-mg
Product Name	Linsitinib
Specifications
Storage Buffer	Off-white solid
Storage Condition	-20°C
Target
Product Information	Linsitinib is a potent and selective dual inhibitor of insulin-like growth factor 1 (IGF-1R) kinase and insulin receptor (InsR) kinase (IC50’s = 35 and 75 nM respectively).1 It has been investigated as a chemotherapeutic in combination with other drugs for various cancers.2-6
Description	CAS Number: 867160-71-2 Chemical Name: 3-[8-Amino-1-(2-phenyl-7-quinolyl)imidazo[1,5-a]pyrazin-3-yl]-1-methyl-cyclobutanol Molecular weight: 421.49 Formula: C26H23N5O Solubility: DMSO (30 mg/ml) Physical Properties: Yellow solid Purity: 98% by HPLC NMR (Conforms)