NU7441
| Overview | |
| Catalog # | bs-83029c-5-mg |
| Product Name | NU7441 |
| Specifications | |
| Storage Buffer | Off-white solid |
| Storage Condition | -20°C |
| Target | |
| Product Information | NU7441 is a potent (IC50 = 13 nM) and selective ATP-competitive inhibitor of DNA-dependent protein kinase (DNA-PK).1,2 It increased the toxicity of ionizing radiation and etoposide on SW620 human colon cancer lines via impeding of DNA double-strand break repair.3 NU7441 also increased the radio/chemosensitivity of various other cancer cell lines.3-6 |
| Description | CAS Number: 503468-95-9 Chemical Name: 8-Dibenzothiophen-4-yl-2-morpholin-4-ylchromen-4-one Molecular weight: 413.49 Formula: C25H19NO3S Solubility: DMSO (10 mg/ml) Physical Properties: Off-white to beige solid Purity: 98% by TLC NMR (Conforms) |
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