Binimetinib
| Overview | |
| Catalog # | bs-83020c-5-mg |
| Product Name | Binimetinib |
| Specifications | |
| Storage Buffer | White solid |
| Storage Condition | -20°C |
| Target | |
| Product Information | Binimetinib (606143-89-9) is a potent (IC50 = 12 nM) and selective allosteric inhibitor of MEK1/2.1,2 Recently approved by the FDA for treatment of melanoma in combination with Encorafenib. Binimetinib has had limited success as monotherapy but has shown promise in combination with other chemotherapeutic agents.3-5 |
| Description | CAS Number: 606143-89-9 Chemical Name: 6-(4-Bromo-2-fluoroanilino)-7-fluoro-N-(2-hydroxyethoxy)-3-methylbenzimidazole-5-carboxamide Molecular weight: 441.23 Formula: C17H15BrF2N4O3 Solubility: DMSO (25 mg/ml) Physical Properties: White solid Purity: 99% by HPLC NMR (Conforms) |
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