AZ3146
| Overview | |
| Catalog # | bs-83014c-5-mg |
| Product Name | AZ3146 |
| Specifications | |
| Storage Buffer | Yellow/brown solid |
| Storage Condition | -20°C |
| Target | |
| Product Information | AZ3146 is a potent (IC50 = 35 nM) and selective monopolar spindle 1 (Mps1/TTK) kinase inhibitor.1 Mps1 has an essential role in the spindle assembly checkpoint, an inhibitory network that restrains anaphase until all kinetochores are stably attached to spindle microtubules during mitosis. AZ3146 decreased hepatocellular carcinoma growth in vitro (SMMC-7721 and BEL-7404 cells).2 |
| Description | CAS Number: 1124329-14-1 Chemical Name: 9-Cyclopentyl-2-[2-methoxy-4-(1-methylpiperidine-4-yl)oxyanilino]-7-methylpurin-8-one Molecular weight: 452.56 Formula: C24H32N6O3S2 Solubility: DMSO (10 mg/ml) Eathnaol (>25 mg/ml) Physical Properties: Off-white solid Purity: 98% by HPLC NMR (conforms) |
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