Raltitrexed
Overview | |
Catalog # | bs-82780c-10-mg |
Product Name | Raltitrexed |
Specifications | |
Storage Buffer | Pale yellow solid |
Storage Condition | -20°C |
Target | |
Product Information | Raltitrexed is an inhibitor of thymidylate synthase with significantly increased potency in many cancer cell lines when compared with 5-fluorouracil.1,2 It is also an inhibitor of the methyltransferase G9a (IC50 = 120 nM) and decreased Aß aggregates in C. elegans indicating therapeutic potential for the treatment of Alzheimer’s disease.3 |
Description | CAS Number: 112887-68-0 Chemical Name: (2S)-2-[[5-[Methyl-[(2-methyl-4-oxo-3H-quinazolin-6-yl)methyl]amino]thiophene-2-carbonyl]amino]pentanedioic acid Molecular weight: 458.49 Formula: C21H22N4O6S Solubility: DMSO (>25 mg/ml) Physical Properties: Pale yellow solid Purity: >98% by HPLC NMR (Conforms) |