GSK620

Overview
Catalog #	bs-82777c-5-mg
Product Name	GSK620
Specifications
Storage Buffer	Off-white to beige solid
Storage Condition	-20°C
Target
Product Information	BET inhibitor 220-fold more selective for BD2 over BD1 (pIC50 BD2 = 7.1; BD1 = 4.8).1 It ameliorated collagen-induced arthritis in a rat model and imiquimod-induced psoriasis in a mouse model.2 GSK620 was also able to reduce hepatic fibrosis, steatosis, and inflammation in a mouse model of non-alcoholic steatohepatitis (NASH).
Description	CAS Number: 2088410-46-0 Chemical Name: 1-Benzyl-5-N-cyclopropyl-3-N-methyl-2-oxopyridine-3,5-dicarboxamide Molecular weight: 325.37 Formula: C18H19N3O3 Solubility: DMSO (25 mg/ml) Physical Properties: White solid Purity: >98% by HPLC NMR (Conforms)