Lomeguatrib

Overview
Catalog #	bs-82759c-10-mg
Product Name	Lomeguatrib
Specifications
Storage Buffer	White solid
Storage Condition	-20°C
Target
Product Information	Lomeguatrib is a potent (IC50 = 9 nM) inhibitor of O6-Methylguanine-DNA Methyltransferase (MGMT), an important DNA repair protein.1 It is currently being investigated in cancers that have acquired resistant to the chemotherapeutic temozolomide2-5, as well as other chemotherapeutics6,7.
Description	CAS Number: 192441-08-0 Chemical Name: 2-Amino-6-[(4-bromo-2-thienyl)methoxy]-9H-purine Molecular weight: 326.17 Formula: C10H8BrN5O3S Solubility: DMSO (10 mg/ml) Physical Properties: Off-white or beige solid Purity: 98% by TLC NMR (Conforms)