TPPU
Overview | |
Catalog # | bs-82680c-5-mg |
Product Name | TPPU |
Specifications | |
Storage Buffer | Yellow solid |
Storage Condition | -20°C |
Target | |
Product Information | TPPU is a potent and selective inhibitor of both murine and human soluble epoxide hydrolase, IC50=2.8 and 3.7 nM respectively.1 It alleviated blood brain barrier damage and attenuated neuronal injury in a mouse intracerebral hemorrhage model2 and displays neuroprotective effects in ischemic injury3. It reduces neuroinflammation in a mouse model of Alzheimer’s disease.4 It improves insulin resistance and reduced hypertension in mouse models.5 Cell permeable and active in vivo. |
Description | CAS Number: 1222780-33-7 Chemical Name: N-[1-(1-Oxopropyl)-4-piperidinyl]-N’-[4-trifluoromethoxy)phenyl]urea Molecular weight: 359.35 Formula: C16H20F3N3O3 Solubility: DMSO (40 mg/ml) Physical Properties: White or off-white solid Purity: >98% by HPLC NMR (Conforms) |