Napabucasin

Overview
Catalog #	bs-82679c-5-mg
Product Name	Napabucasin
Specifications
Storage Buffer	Yellow solid
Storage Condition	-20°C
Target
Product Information	Inhibits gene transcription driven by STAT3. Inhibits cancer cell stemness gene expression and blocks spherogenesis of stemness-high cancer cells isolated from a variety of cancer types.1 Effective antitumor agent as a monotherapy or in combination with other agents such as taxol in mouse models.2 Clinical trials have demonstrated encouraging anti-tumor activity with the potential to suppress metastasis and prevent relapse in patients with various types of cancer.2,3 Overcomes cisplatin resistance in non-small cell lung cancer.4
Description	CAS Number: 83280-65-3 Chemical Name: 2-Acetylnsphtho[2,3-b]furan-4,9-dione Molecular weight: 240.21 Formula: C14H8O4 Solubility: DMSO (20 mg/ml) Physical Properties: Yellow solid Purity: 98% by TLC NMR (Conforms)