Lenvatinib

Overview
Catalog #	bs-82664c-5-mg
Product Name	Lenvatinib
Specifications
Storage Buffer	White solid
Storage Condition	-20°C
Target
Product Information	A potent inhibitor of VEGFR2 and R3, IC50s=4.0 and 5.2 nM respectively.1 Also inhibits VEGFR1, FGFR1, PDGFR3b and Kit, IC50s=22, 46, 39 and 100 nM respectively.1 Suppresses lymph node and lung metastasis in human mammary breast tumor model.2 Suppresses tumor cell migration and invasion.3 Inhibits angiogenesis.4
Description	CAS Number: 417716-92-8 Chemical Name: 4-[3-Chloro-4-[[(cyclopropylamino)carbonyl]amino]phenoxy]-7-methoxy-6-quinolinecarboxamide Molecular weight: 426.85 Formula: C21H19ClN4O4 Solubility: DMSO (20 mg/ml) Physical Properties: White solid Purity: 98% by HPLC, NMR (Conforms)