Kenpaullone

Overview
Catalog #	bs-82634c-5-mg
Product Name	Kenpaullone
Specifications
Storage Buffer	White solid
Storage Condition	-20°C
Target
Product Information	Inhibits GSK-3β (IC50=0.23 µM) as well as several cyclin-dependent kinases (CDKs), IC50=0.4, 0.68 and 0.85 µM for cdk1, cdk2 and cdk5 respectively.1-3 Induces pluripotent stem cells from somatic cells4 and increases direct neural conversion of human fibroblasts5 when used with other small molecules. Inhibits Kruppel-Like Factor 4 (KLF4) reducing autoimmune arthritis in the collagen-induced arthritis mouse model.6
Description	CAS Number: 142273-20-9 Chemical Name: 9-Bromo-7,12-dihydro-indolo[3,2-d]benzazepine-6(5H-one Molecular weight: 327.18 Formula: C16H11BrN2O Solubility: DMSO (35 mg/ml) Physical Properties: Off-white solid Purity: >98% by TLC, NMR (Conforms)