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AH-7614

Overview
Catalog # bs-80314C
Product Name AH-7614
Specifications
Storage Buffer powder
Storage Condition -20°C
Target
Product Information Molecular Weight:351.43

Formula:C20H17NO3S

Purity:>98%

Solubility:Soluble in DMSO (up to 50 mg/ml) or in Ethanol (up to 8 mg/ml with warming).

Chemical Name:4-Methyl-N-9H-xanthen-9-yl-benzenesulfonamide

Description Selective antagonist at free fatty acid receptor 4 (FFA4), also known as GPR120. pIC50s= 7.1 and <4.6 for FFA4 and FFA1 respectively. Inhibits linoleic acid and GSK137647A-induced intracellular calcium increase in U2OS osteosarcoma cells expressing GPR120.1 Has been used to probe the GPR120-mediated effects of fatty acids on a GnRH-synthesizing neuronal cell model.2