Salermide

Overview
Catalog #	bs-80309C
Product Name	Salermide
Specifications
Storage Buffer	powder
Storage Condition	-20°C
Target
Product Information	Molecular Weight:394.47 Formula:C26H22N2O2 Purity:>98% Solubility:Soluble in DMSO (up to 40 mg/ml), in DMF (up to 30 mg/ml) or in Ethanol (up to 10 mg/ml with warming) Chemical Name:N-[3-[[(2-Hydroxy-1-naphthalenyl)methylene]amino]phenyl]-α-methylbenzeneacetamide
Description	SIRT1 and SIRT2 inhibitor. Exhibits a stronger inhibitory effect on SIRT2 than on SIRT1 in vitro. Induces the reactivation of proapoptotic genes repressed by SIRT1 and causes massive apoptosis in cancer cells within 24 hours.1 Displays protective effect in nematodes expressing muscular dystrophy protein.2 Promotes neuronal apoptosis confirming the protective effect of SIRT1.3