RVX-208
| Overview | |
| Catalog # | bs-80291C |
| Product Name | RVX-208 |
| Specifications | |
| Storage Buffer | powder |
| Storage Condition | -20°C |
| Target | |
| Product Information | Molecular Weight:370.41 Formula:C20H22N2O5 Purity:>98% Solubility:Soluble in DMSO (up to 75 mg/ml) or in Ethanol (up to 4 mg/ml). Chemical Name:2-[4-(2-hydroxyethoxy)-3,5-dimethylphenyl]-5,7-dimethoxy-4(3H)-quinzolinone |
| Description | RVX-208 is a potent BET bromodomain antagonist with IC50 of 0.510 μM for BD2, with approximately 170-fold selectivity over BD11,2. Increases apolipoprotein A-1 and HDL cholesterol in vitro and in vivo3. Reduces atherosclerosis4. |
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