Stavudine

Overview
Catalog #	bs-80156C
Product Name	Stavudine
Specifications
Storage Buffer	powder
Storage Condition	-20°C
Target
Product Information	Molecular Weight:224.2 Formula:C10H12N2O4 Purity: Solubility:Soluble in DMSO (up to 20 mg/ml), or in Water (up to 20 mg/ml). Chemical Name:2',3'-Didehydro-3'-deoxy-thymidine
Description	Thymidine derivative that acts as an HIV nucleoside reverse transcriptase inhibitor (NRTI) (EC50 = 8.8 nM for HIV-1 replication in human PBMCs)1,2. Down-modulates P2X7-mediated NLRP3 inflammasome activation independent of reverse transcriptase inhibition3. Reduces production of IL-18 and caspase-1 and stimulates Aβ-induced autophagy in macrophages4.