Methotrexate
| Overview | |
| Catalog # | bs-80155C |
| Product Name | Methotrexate |
| Specifications | |
| Storage Buffer | powder |
| Storage Condition | -20°C |
| Target | |
| Product Information | Molecular Weight:554.4 Formula:C20H22N8O5 ∙ xH2O Purity:>98% Solubility:Soluble in DMSO (up to 45 mg/ml). Chemical Name:N-[4-[[(2,4-Diamino-6-pteridinyl)methyl]methylamino]benzoyl]-L-glutamic acid |
| Description | A synthetic folic acid analog with immunosuppressant and cancer chemotherapeutic activity1. Inhibits thymidylate synthetase and de novo purine synthesis2,3. Displays beneficial effects in rheumatoid arthritis by inhibiting the production of cytokines induced by T-cell activation4 and stimulation of adenosine release5. It is the classic disease-modifying antirheumatic drug (DMARD)6 |
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