Overview |
bs-22560R-Biotin |
ZNT8 Polyclonal Antibody, Biotin Conjugated |
IHC-P |
Rat |
Human, Mouse |
Specifications |
Biotin |
Rabbit |
KLH conjugated synthetic peptide derived from human ZNT8 |
1-100/369 |
Polyclonal |
IgG |
1ug/ul |
Purified by Protein A. |
Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
Store at -20°C for 12 months. |
Target |
169026 |
Q8IWU4 |
Cytoplasm, Cell membrane |
SLC30A8; solute carrier family 30 (zinc transporter), member 8; Solute carrier family 30 member 8; Zinc transporter 8; zinc transporter ZnT-8; ZnT-8; ZNT 8; ZNT8_HUMAN. |
ZNT8 is a zinc efflux transporter involved in the accumulation of zinc in intracellular vesicles. This gene is expressed at a high level only in the pancreas, particularly in islets of Langerhans. The encoded protein colocalizes with insulin in the secretory pathway granules of the insulin-secreting INS-1 cells. Allelic variants of this gene exist that confer susceptibility to diabetes mellitus, noninsulin-dependent (NIDDM). Several transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Mar 2010]. |
Application Dilution |
IHC-P |
1:200-400 |