IDH1 Monoclonal Antibody + Cell Lysate Kit
Applications
Reactivity
Overview | |
Catalog # | bsm-90019R |
Product Name | IDH1 Monoclonal Antibody + Cell Lysate Kit |
Applications | WB, FCM, IC |
Specificity | Knockdown Validated |
Reactivity | Human, Mouse, Rat |
Specifications | |
Conjugation | Unconjugated |
Host | Rabbit |
Source | A synthesized peptide derived from human IDH1 |
Immunogen Range | 1-70/414 |
Clonality | Monoclonal |
Clone # | 23GB2105 |
Isotype | IgG |
Concentration | Lot dependent |
Purification | Affinity Purified |
Storage Buffer | Supplied in PBS (pH 7.4) containing 50% glycerol, and 0.02% sodium azide. |
Storage Condition | -20 °C |
Target | |
Gene ID | 3417 |
Swiss Prot | O75874 |
Synonyms | IDH1; Isocitrate Dehydrogenase (NADP(+)) 1; Isocitrate Dehydrogenase (NADP(+)) 1, Cytosolic; Isocitrate Dehydrogenase 1 (NADP+), Soluble; Isocitrate Dehydrogenase [NADP] Cytoplasmic; Oxalosuccinate Decarboxylase; NADP(+)-Specific ICDH; EC 1.1.1.42; PICD; IDH; NADP-Dependent Isocitrate Dehydrogenase, Peroxisomal; NADP-Dependent Isocitrate Dehydrogenase, Cytosolic; Epididymis Secretory Sperm Binding Protein; Cytosolic NADP-Isocitrate Dehydrogenase; Isocitrate Dehydrogenase 1 (NADP+); Epididymis Secretory Protein Li 26; Epididymis Luminal Protein 216; HEL-S-26; HEL-216; IDCD; IDPC; IDPc; IDP |
Background | Catalyzes the NADP+-dependent oxidative decarboxylation of isocitrate (D-threo-isocitrate) to 2-ketoglutarate (2-oxoglutarate), which is required by other enzymes such as the phytanoyl-CoA dioxygenase. Plays a critical role in the generation of NADPH, an important cofactor in many biosynthesis pathways. May act as a corneal epithelial crystallin and may be involved in maintaining corneal epithelial transparency (By similarity).. Cell Line: HeLa Knockdown technology: shRNA Knockdown |
Application Dilution | |
WB | : 1:1000-1:5000 |
FCM | FCM: 1:2000 |
IC | IC: 1:1000 |