Overview |
bsm-62970r-100ul |
Phospho-RPS6KB1 (Thr421/Ser424) Monoclonal Antibody |
WB, IP |
Human, Rat |
Specifications |
Unconjugated |
Rabbit |
KLH conjugated synthetic peptide derived from human p70 S6 Kinase around the phosphorylation site of T421/S424 |
Thr421/Ser424 |
Monoclonal |
Recombinant |
IgG |
1ug/ul |
Purified by Protein A. |
10mM phosphate buffered saline(pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% sodium azide and 50% glycerol. |
Shipped at 4°. Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
Target |
6198 |
P23443 |
Cytoplasm, Nucleus |
EC 2.7.11.1, KS6B1, P70-S6K, RPS6KB1, Ribosomal protein S6 kinase, Ribosomal protein S6 kinase, 70kDa, polypeptide 1, S6K, kinase p70S6K, p70-S6K. |
Acts to integrate nutrient and growth factor signals in regulation of protein synthesis, cell proliferation, cell growth, cell cycle progression and cell survival. Downstream effector of the mTOR signaling pathway. |
Application Dilution |
WB |
:1:1000-1:2000 |
IP |
IP:1:20-1:50 |