Phospho-RPS6KB1 (Thr421/Ser424) Monoclonal Antibody

Overview
Catalog #	bsm-62970r-100ul
Product Name	Phospho-RPS6KB1 (Thr421/Ser424) Monoclonal Antibody
Applications	WB, IP
Reactivity	Human, Rat
Specifications
Conjugation	Unconjugated
Host	Rabbit
Source	KLH conjugated synthetic peptide derived from human p70 S6 Kinase around the phosphorylation site of T421/S424
Modification Site	Thr421/Ser424
Clonality	Monoclonal
Clone #	Recombinant
Isotype	IgG
Concentration	1ug/ul
Purification	Purified by Protein A.
Storage Buffer	10mM phosphate buffered saline(pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% sodium azide and 50% glycerol.
Storage Condition	Shipped at 4°. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
Target
Gene ID	6198
Swiss Prot	P23443
Subcellular location	Cytoplasm, Nucleus
Synonyms	EC 2.7.11.1, KS6B1, P70-S6K, RPS6KB1, Ribosomal protein S6 kinase, Ribosomal protein S6 kinase, 70kDa, polypeptide 1, S6K, kinase p70S6K, p70-S6K.
Background	Acts to integrate nutrient and growth factor signals in regulation of protein synthesis, cell proliferation, cell growth, cell cycle progression and cell survival. Downstream effector of the mTOR signaling pathway.
Application Dilution
WB	:1:1000-1:2000
IP	IP:1:20-1:50