Overview |
bsm-62834r-percp-cy55-100ul |
Phospho-SHIP1 (Tyr1022) Recombinant Monoclonal Antibody, PerCP-Cy5.5 Conjugated |
WB, IF(ICC) |
Human |
Specifications |
PerCP-Cy5.5 |
Rabbit |
KLH conjugated synthetic peptide derived from human INPP5D around the phosphorylation site of Y1022 |
Tyr1022 |
Monoclonal |
Recombinant |
IgG |
Lot dependent |
Purified by Protein A. |
Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles. |
Target |
3635 |
Q92835 |
Cytoplasm, Cell membrane |
Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 1; Inositol polyphosphate-5-phosphatase of 145 kDa; SIP-145; SH2 domain-containing inositol 5'-phosphatase 1; SHIP-1; p150Ship; hp51CN; INPP5D; SHIP. |
Phosphatidylinositol (PtdIns) phosphatase that specifically hydrolyzes the 5-phosphate of phosphatidylinositol-3,4,5-trisphosphate (PtdIns(3,4,5)P3) to produce PtdIns(3,4)P2, thereby negatively regulating the PI3K (phosphoinositide 3-kinase) pathways. |
Application Dilution |
WB |
1:300-5000 |
IF(ICC) |
1:50-200 |