HN1 Monoclonal Antibody
Applications
Reactivity
Overview | |
Catalog # | bsm-62795r-100ul |
Product Name | HN1 Monoclonal Antibody |
Applications | WB, FCM |
Reactivity | Human, Mouse, Rat |
Specifications | |
Conjugation | Unconjugated |
Host | Rabbit |
Source | KLH conjugated synthetic peptide derived from human JPT1 |
Clonality | Monoclonal |
Clone # | Recombinant |
Isotype | IgG |
Concentration | 1ug/ul |
Purification | Purified by Protein A. |
Storage Buffer | 10mM phosphate buffered saline(pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% sodium azide and 50% glycerol. |
Storage Condition | Shipped at 4°. Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
Target | |
Gene ID | 51155 |
Swiss Prot | Q9UK76 |
Subcellular location | Nucleus |
Synonyms | ARM2; HN1; HN1A. |
Background | Modulates negatively AKT-mediated GSK3B signaling.Induces CTNNB1 'Ser-33' phosphorylation and degradation through the suppression of the inhibitory 'Ser-9' phosphorylation of GSK3B, which represses the function of the APC:CTNNB1:GSK3B complex and the interaction with CDH1/E-cadherin in adherent junctions. |
Application Dilution | |
WB | :1:1000-1:2000 |
FCM | FCM:1:20-1:100 |