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GLCNE Recombinant Monoclonal Antibody, PE-Cy5.5 Conjugated

Applications

  • WB

Reactivity

  • Human
Overview
Catalog # bsm-62710r-pe-cy55-100ul
Product Name GLCNE Recombinant Monoclonal Antibody, PE-Cy5.5 Conjugated
Applications WB
Reactivity Human
Specifications
Conjugation PE-Cy5.5
Host Rabbit
Source KLH conjugated synthetic peptide derived from human GNE
Clonality Monoclonal
Clone # Recombinant
Isotype IgG
Concentration Lot dependent
Purification Purified by Protein A.
Storage Buffer Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Storage Condition Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Target
Gene ID 10020
Swiss Prot Q9Y223
Subcellular location Cytoplasm
Synonyms DMRV; GNE; IBM2; ManAc kinase; Uae1;GLCNE.
Background Bifunctional enzyme that possesses both UDP-N-acetylglucosamine 2-epimerase and N-acetylmannosamine kinase activities, and serves as the initiator of the biosynthetic pathway leading to the production of N-acetylneuraminic acid (NeuAc), a critical precursor in the synthesis of sialic acids. By catalyzing this pivotal and rate-limiting step in sialic acid biosynthesis, this enzyme assumes a pivotal role in governing the regulation of cell surface sialylation.
Application Dilution
WB 1:300-5000