CD133 Monoclonal Antibody

Overview
Catalog #	bsm-62477r-100ul
Product Name	CD133 Monoclonal Antibody
Applications	WB, IHC-P, IHC-F, IF
Reactivity	Human
Specifications
Conjugation	Unconjugated
Host	Rabbit
Source	KLH conjugated synthetic peptide derived from human CD133
Clonality	Monoclonal
Clone #	Recombinant
Isotype	IgG
Concentration	1ug/ul
Purification	Purified by Protein A.
Storage Buffer	10mM phosphate buffered saline(pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% sodium azide and 50% glycerol.
Storage Condition	Shipped at 4°. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
Target
Gene ID	8842
Swiss Prot	O43490
Synonyms	AC133; CD133; CORD12; hProminin; MCDR2; PROM1; Prominin like 1; Prominin1; PROML1; RP41; STGD4
Background	May play a role in cell differentiation, proliferation and apoptosis. Binds cholesterol in cholesterol-containing plasma membrane microdomains and may play a role in the organization of the apical plasma membrane in epithelial cells. During early retinal development acts as a key regulator of disk morphogenesis. Involved in regulation of MAPK and Akt signaling pathways. In neuroblastoma cells suppresses cell differentiation such as neurite outgrowth in a RET-dependent manner.
Application Dilution
WB	:1:1000-1:2000
IHC-P	IHC-P:1:100-1:200
IHC-F	IHC-F:1:100-1:200
IF	IF:1:100-1:200