| Overview |
| bsm-62437r-100ul |
| NPC1 Recombinant Monoclonal Antibody |
| WB, FCM, IHC-P, IHC-F, IF(ICC), IF |
| Human, Mouse, Rat |
| Specifications |
| Unconjugated |
| Rabbit |
| KLH conjugated synthetic peptide derived from human Niemann pick C1 |
| Monoclonal |
| Recombinant |
| IgG |
| Lot dependent |
| Purified by Protein A. |
| 10mM phosphate buffered saline(pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% sodium azide and 50% glycerol. |
| Shipped at 4°. Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Target |
| 4864 |
| O15118 |
| Cytoplasm, Cell membrane |
| Niemann Pick C1 protein precursor; NPC; NPC1. |
| Intracellular cholesterol transporter which acts in concert with NPC2 and plays an important role in the egress of cholesterol from the endosomal/lysosomal compartment.Unesterified cholesterol that has been released from LDLs in the lumen of the late endosomes/lysosomes is transferred by NPC2 to the cholesterol-binding pocket in the N-terminal domain of NPC1. |
| Application Dilution |
| WB |
1:300-5000 |
| FCM |
1:20-100 |
| IHC-P |
1:200-400 |
| IHC-F |
1:100-500 |
| IF(ICC) |
1:50-200 |
| IF |
|
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