PITX3 Monoclonal Antibody

Overview
Catalog #	bsm-62389r-100ul
Product Name	PITX3 Monoclonal Antibody
Applications	WB, FCM, IP
Reactivity	Human, Mouse, Rat
Specifications
Conjugation	Unconjugated
Host	Rabbit
Source	KLH conjugated synthetic peptide derived from human Pituitary homeobox 3
Clonality	Monoclonal
Clone #	Recombinant
Isotype	IgG
Concentration	1ug/ul
Purification	Purified by Protein A.
Storage Buffer	10mM phosphate buffered saline(pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% sodium azide and 50% glycerol.
Storage Condition	Shipped at 4°. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
Target
Gene ID	5309
Swiss Prot	O75364
Subcellular location	Nucleus
Synonyms	Pitx3; PTX3.
Background	Transcriptional regulator which is important for the differentiation and maintenance of meso-diencephalic dopaminergic (mdDA) neurons during development. In addition to its importance during development, it also has roles in the long-term survival and maintenance of the mdDA neurons. Activates NR4A2/NURR1-mediated transcription of genes such as SLC6A3, SLC18A2, TH and DRD2 which are essential for development of mdDA neurons.
Application Dilution
WB	:1:1000-1:2000
FCM	FCM:1:20-1:100
IP	IP:1:20-1:50