Overview |
bsm-62038r-100ul |
EBF1 Monoclonal Antibody |
WB |
Human, Mouse |
Specifications |
Unconjugated |
Rabbit |
KLH conjugated synthetic peptide derived from human COE1 |
Monoclonal |
Recombinant |
IgG |
1ug/ul |
Purified by Protein A. |
10mM phosphate buffered saline(pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% sodium azide and 50% glycerol. |
Shipped at 4°. Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
Target |
1879 |
Q9UH73 |
Nucleus |
COE1; EBF; Ebf1; O/E 1; OE1; OLF1. |
Key pioneer transcription factor of B-cell specification and commitment.Recognizes variations of the palindromic sequence 5'-ATTCCCNNGGGAATT-3'. Operates in a transcription factor network to activate B-cell-specific genes and repress genes associated with alternative cell fates. For instance, positively regulates many B-cell specific genes including BCR or CD40 while repressing genes that direct cells into alternative lineages, including GATA3 and TCF7 for the T-cell lineage. |
Application Dilution |
WB |
:1:1000-1:2000 |