Overview |
bsm-61981r-pe-cy7-100ul |
p150 CAF1 Recombinant Antibody, PE-Cy7 Conjugated |
WB, FCM |
Human |
Specifications |
PE-Cy7 |
Rabbit |
KLH conjugated synthetic peptide derived from human CAF 1 subunit A |
Recombinant |
IgG |
Lot dependent |
Purified by Protein A. |
Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles. |
Target |
10036 |
Q13111 |
Nucleus |
CAF; CAF1; CAF1P150; CHAF1A; DCAF1; hp15; P150. |
Core component of the CAF-1 complex, a complex that is thought to mediate chromatin assembly in DNA replication and DNA repair. Assembles histone octamers onto replicating DNA in vitro. CAF-1 performs the first step of the nucleosome assembly process, bringing newly synthesized histones H3 and H4 to replicating DNA; histones H2A/H2B can bind to this chromatin precursor subsequent to DNA replication to complete the histone octamer. It may play a role in heterochromatin maintenance in proliferating cells by bringing newly synthesized cbx proteins to heterochromatic DNA replication foci. |
Application Dilution |
WB |
1:300-5000 |
FCM |
1:20-100 |