| Overview |
| bsm-61966r-apc-100ul |
| TREX1 Recombinant Antibody, APC Conjugated |
| WB, IF(ICC) |
| Human |
| Specifications |
| APC |
| Rabbit |
| KLH conjugated synthetic peptide derived from human TREX1 |
| Recombinant |
| IgG |
| Lot dependent |
| Purified by Protein A. |
| Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles. |
| Target |
| 11277 |
| Q9NSU2 |
| AGS1; AGS5; CRV; DNase III; DRN3; HERNS; TREX1. |
| Major cellular 3'-to-5' DNA exonuclease which digests single-stranded DNA (ssDNA) and double-stranded DNA (dsDNA) with mismatched 3' termini.Prevents cell-intrinsic initiation of autoimmunity.Acts by metabolizing DNA fragments from endogenous retroelements, including L1, LTR and SINE elements. |
| Application Dilution |
| WB |
1:300-5000 |
| IF(ICC) |
1:50-200 |
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