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DARC Recombinant Monoclonal Antibody, Cy3 Conjugated

Applications

  • WB
  • FCM
  • IF(ICC)

Reactivity

  • Human
  • Mouse
Overview
Catalog # bsm-61907r-cy3-100ul
Product Name DARC Recombinant Monoclonal Antibody, Cy3 Conjugated
Applications WB, FCM, IF(ICC)
Reactivity Human, Mouse
Specifications
Conjugation Cy3
Host Rabbit
Source KLH conjugated synthetic peptide derived from human Atypical chemokine receptor 1
Clonality Monoclonal
Clone # Recombinant
Isotype IgG
Concentration Lot dependent
Purification Purified by Protein A.
Storage Buffer Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Storage Condition Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Target
Gene ID 2532
Swiss Prot Q16570
Subcellular location Cell membrane
Synonyms CCBP1; CD234; DARC; Dfy; FY; GPD; GpFy; WBCQ1.
Background Atypical chemokine receptor that controls chemokine levels and localization via high-affinity chemokine binding that is uncoupled from classic ligand-driven signal transduction cascades, resulting instead in chemokine sequestration, degradation, or transcytosis. Also known as interceptor (internalizing receptor) or chemokine-scavenging receptor or chemokine decoy receptor. Has a promiscuous chemokine-binding profile, interacting with inflammatory chemokines of both the CXC and the CC subfamilies but not with homeostatic chemokines.
Application Dilution
WB 1:300-5000
FCM 1:20-100
IF(ICC) 1:50-200