Overview |
bsm-61838r-100ul |
SMURF2 Monoclonal Antibody |
WB |
Human, Mouse, Rat |
Specifications |
Unconjugated |
Rabbit |
KLH conjugated synthetic peptide derived from human SMURF2 |
Monoclonal |
Recombinant |
IgG |
1ug/ul |
Purified by Protein A. |
10mM phosphate buffered saline(pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% sodium azide and 50% glycerol. |
Shipped at 4°. Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
Target |
64750 |
Q9HAU4 |
Cytoplasm, Nucleus, Cell membrane |
hSMURF2; SMUF2_HUMAN; Smurf2. |
E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates.Interacts with SMAD7 to trigger SMAD7-mediated transforming growth factor beta/TGF-beta receptor ubiquitin-dependent degradation, thereby down-regulating TGF-beta signaling. |
Application Dilution |
WB |
:1:1000-1:2000 |