Overview |
bsm-61756r-100ul |
PU.1/Spi1 Monoclonal Antibody |
WB, FCM, IHC-P, IHC-F, IF |
Human |
Specifications |
Unconjugated |
Rabbit |
KLH conjugated synthetic peptide derived from human SPI1 |
Monoclonal |
Recombinant |
IgG |
1ug/ul |
Purified by Protein A. |
10mM phosphate buffered saline(pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% sodium azide and 50% glycerol. |
Shipped at 4°. Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
Target |
6688 |
P17947 |
Nucleus |
oncogene spi1; PU.1; SFPI1; SPI 1; SPI A; Spi1. |
Pioneer transcription factor, which controls hematopoietic cell fate by decompacting stem cell heterochromatin and allowing other transcription factors to enter otherwise inaccessible genomic sites. Once in open chromatin, can directly control gene expression by binding genetic regulatory elements and can also more broadly influence transcription by recruiting transcription factors, such as interferon regulatory factors (IRFs), to otherwise inaccessible genomic regions. |
Application Dilution |
WB |
:1:1000-1:2000 |
FCM |
FCM:1:20-1:100 |
IHC-P |
IHC-P:1:100-1:200 |
IHC-F |
IHC-F:1:100-1:200 |
IF |
IF:1:100-1:200 |