Overview |
bsm-61694r-biotin-100ul |
KSR1 Recombinant Antibody, Biotin Conjugated |
WB, IHC-P, IHC-F |
Human, Mouse |
Specifications |
Biotin |
Rabbit |
KLH conjugated synthetic peptide derived from human KSR1 |
Recombinant |
IgG |
Lot dependent |
Purified by Protein A. |
Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
Store at -20°C for 12 months. |
Target |
8844 |
Q8IVT5 |
Cytoplasm, Cell membrane |
BKSR1; dKsr; EK31; KSR; KSR1; RSU2; SR31. |
Part of a multiprotein signaling complex which promotes phosphorylation of Raf family members and activation of downstream MAP kinases.Independently of its kinase activity, acts as MAP2K1/MEK1 and MAP2K2/MEK2-dependent allosteric activator of BRAF; upon binding to MAP2K1/MEK1 or MAP2K2/MEK2, dimerizes with BRAF and promotes BRAF-mediated phosphorylation of MAP2K1/MEK1 and/or MAP2K2/MEK2. |
Application Dilution |
WB |
1:300-5000 |
IHC-P |
1:200-400 |
IHC-F |
1:100-500 |