| Overview |
| bsm-61675r-biotin-100ul |
| TRIM25 Recombinant Monoclonal Antibody, Biotin Conjugated |
| WB, IHC-P, IHC-F, IP |
| Human, Mouse, Rat |
| Specifications |
| Biotin |
| Rabbit |
| KLH conjugated synthetic peptide derived from human TRIM25 |
| Monoclonal |
| Recombinant |
| IgG |
| Lot dependent |
| Purified by Protein A. |
| Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Store at -20°C for 12 months. |
| Target |
| 7706 |
| Q14258 |
| Cytoplasm, Nucleus |
| EFP; RNF147; TRI25; TRIM 25; Trim25; Z147; ZNF147. |
| Functions as an ubiquitin E3 ligase and as an ISG15 E3 ligase. Involved in innate immune defense against viruses by mediating ubiquitination of DDX58. Mediates 'Lys-63'-linked polyubiquitination of the DDX58 N-terminal CARD-like region which is crucial for triggering the cytosolic signal transduction that leads to the production of interferons in response to viral infection. |
| Application Dilution |
| WB |
1:300-5000 |
| IHC-P |
1:200-400 |
| IHC-F |
1:100-500 |
| IP |
1-2ug |
Powered by Bioz