FADD Monoclonal Antibody

Overview
Catalog #	bsm-61661r-100ul
Product Name	FADD Monoclonal Antibody
Applications	WB, FCM, IHC-P, IHC-F, IF
Reactivity	Mouse
Specifications
Conjugation	Unconjugated
Host	Rabbit
Source	KLH conjugated synthetic peptide derived from mouse Fadd
Clonality	Monoclonal
Clone #	Recombinant
Isotype	IgG
Concentration	1ug/ul
Purification	Purified by Protein A.
Storage Buffer	10mM phosphate buffered saline(pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% sodium azide and 50% glycerol.
Storage Condition	Shipped at 4°. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
Target
Gene ID	14082
Swiss Prot	Q61160
Subcellular location	Cytoplasm
Synonyms	FADD protein; GIG3; Growth inhibiting gene 3 protein; Mediator of receptor induced toxicity; MORT1.
Background	Apoptotic adapter molecule that recruits caspases CASP8 or CASP10 to the activated FAS/CD95 or TNFRSF1A/TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs CASP8 proteolytic activation. Active CASP8 initiates the subsequent cascade of caspases mediating apoptosis. Involved in interferon-mediated antiviral immune response, playing a role in the positive regulation of interferon signaling.
Application Dilution
WB	:1:1000-1:2000
FCM	FCM:1:20-1:100
IHC-P	IHC-P:1:100-1:200
IHC-F	IHC-F:1:100-1:200
IF	IF:1:100-1:200