LPA1 Monoclonal Antibody

Overview
Catalog #	bsm-61606r-100ul
Product Name	LPA1 Monoclonal Antibody
Applications	WB, IHC-P, IHC-F, IP, IF
Reactivity	Human
Specifications
Conjugation	Unconjugated
Host	Rabbit
Source	KLH conjugated synthetic peptide derived from human LPA receptor 1
Clonality	Monoclonal
Clone #	Recombinant
Isotype	IgG
Concentration	1ug/ul
Purification	Purified by Protein A.
Storage Buffer	10mM phosphate buffered saline(pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% sodium azide and 50% glycerol.
Storage Condition	Shipped at 4°. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
Target
Gene ID	1902
Swiss Prot	Q92633
Subcellular location	Cytoplasm, Cell membrane
Synonyms	Lysophosphatidic acid receptor 1; LPA receptor 1; LPA-1; Lysophosphatidic acid receptor Edg-2; LPAR1; EDG2; LPA1.
Background	Plays a role in the reorganization of the actin cytoskeleton, cell migration, differentiation and proliferation, and thereby contributes to the responses to tissue damage and infectious agents. Activates downstream signaling cascades via the G(i)/G(o), G12/G13, and G(q) families of heteromeric G proteins. Signaling inhibits adenylyl cyclase activity and decreases cellular cAMP levels.
Application Dilution
WB	:1:1000-1:2000
IHC-P	IHC-P:1:100-1:200
IHC-F	IHC-F:1:100-1:200
IP	IP:1:20-1:50
IF	IF:1:100-1:200