| Overview |
| bsm-61566r-100ul |
| CYP3A4 Monoclonal Antibody |
| WB, IHC-P, IHC-F, IP, IF |
| Human |
| Specifications |
| Unconjugated |
| Rabbit |
| KLH conjugated synthetic peptide derived from human Cytochrome P450 3A4 |
| Monoclonal |
| Recombinant |
| IgG |
| 1ug/ul |
| Purified by Protein A. |
| 10mM phosphate buffered saline(pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% sodium azide and 50% glycerol. |
| Shipped at 4°. Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Target |
| 1576 |
| P08684 |
| Cytoplasm, Cell membrane |
| CYP3A4; CYPIIIA3; CYPIIIA4; Cytochrome P450 3A3; Cytochrome P450 HLp; Cytochrome P450 NF-25; Cytochrome P450-PCN1; Nifedipine oxidase. |
| A cytochrome P450 monooxygenase involved in the metabolism of sterols, steroid hormones, retinoids and fatty acids. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate, and reducing the second into a water molecule, with two electrons provided by NADPH via cytochrome P450 reductase (NADPH--hemoprotein reductase). Catalyzes the hydroxylation of carbon-hydrogen bonds. |
| Application Dilution |
| WB |
:1:1000-1:2000 |
| IHC-P |
IHC-P:1:100-1:200 |
| IHC-F |
IHC-F:1:100-1:200 |
| IP |
IP:1:20-1:50 |
| IF |
IF:1:100-1:200 |
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