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ITK Monoclonal Antibody

Applications

  • WB
  • FCM
  • IHC-P
  • IHC-F
  • IF

Reactivity

  • Human
Overview
Catalog # bsm-61531r-100ul
Product Name ITK Monoclonal Antibody
Applications WB, FCM, IHC-P, IHC-F, IF
Reactivity Human
Specifications
Conjugation Unconjugated
Host Rabbit
Source KLH conjugated synthetic peptide derived from human ITK
Clonality Monoclonal
Clone # Recombinant
Isotype IgG
Concentration 1ug/ul
Purification Purified by Protein A.
Storage Buffer 10mM phosphate buffered saline(pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% sodium azide and 50% glycerol.
Storage Condition Shipped at 4°. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
Target
Gene ID 3702
Swiss Prot Q08881
Subcellular location Nucleus
Synonyms EMT; Homolog of mouse T cell itk/tsk; IL 2 inducible T cell kinase; Itk; Kinase EMT; LPFS1; LYK; PSCTK2; T cell specific kinase; TSK; Tyrosine protein kinase ITK/TSK.
Background Interleukin-2 inducible T-cell kinase (Itk, Emt or Tsk) is a member of the non-receptor protein tyrosine kinases. Family members of Itk include Tec, Btk, Rlk and Bmx and are all defined by a common structure: an amino-terminal PH domain, a Tec-homology domain and a SH3 and SH2 domain followed by a carboxy-terminal kinase domain. Tec, Rlk and Itk are expressed in T cells and activated in response to T cell receptor (TCR) engagement.
Application Dilution
WB :1:1000-1:2000
FCM FCM:1:20-1:100
IHC-P IHC-P:1:100-1:200
IHC-F IHC-F:1:100-1:200
IF IF:1:100-1:200