MGMT Monoclonal Antibody
Applications
Reactivity
Overview | |
Catalog # | bsm-61358r-100ul |
Product Name | MGMT Monoclonal Antibody |
Applications | WB, IHC-P, IHC-F, IF |
Reactivity | Human |
Specifications | |
Conjugation | Unconjugated |
Host | Rabbit |
Source | KLH conjugated synthetic peptide derived from human MGMT |
Clonality | Monoclonal |
Clone # | Recombinant |
Isotype | IgG |
Concentration | 1ug/ul |
Purification | Purified by Protein A. |
Storage Buffer | 10mM phosphate buffered saline(pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% sodium azide and 50% glycerol. |
Storage Condition | Shipped at 4°. Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
Target | |
Gene ID | 4255 |
Swiss Prot | P16455 |
Subcellular location | Nucleus |
Synonyms | MGMT |
Background | Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated. |
Application Dilution | |
WB | :1:1000-1:2000 |
IHC-P | IHC-P:1:100-1:200 |
IHC-F | IHC-F:1:100-1:200 |
IF | IF:1:100-1:200 |