Overview |
bsm-61246r-apc-cy5-100ul |
hnRNP K Recombinant Monoclonal Antibody, APC-Cy5 Conjugated |
WB, IF(ICC) |
Human, Mouse, Rat |
Specifications |
APC-Cy5 |
Rabbit |
KLH conjugated synthetic peptide derived from human hnRNP K |
Monoclonal |
Recombinant |
IgG |
Lot dependent |
Purified by Protein A. |
Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles. |
Target |
3190 |
P61978 |
Cytoplasm, Nucleus |
65 kDa phosphoprotein; CSBP; TUNP; HNRNPK; HNRPK; DC-stretch binding protein; hnRNP-K. |
Facilitate pre-mRNA processing and transport of mRNA from the nucleus to cytoplasm. hnRNP K contains three unique structural motifs termed KH domains that bind poly(C) DNA and RNA sequences. Intricate architecture enables hnRNP K to facilitate mRNA biosynthesis, transcriptional regulation, and signal transduction. Research studies have shown that cytoplasmic hnRNP K expression is increased in oral squamous cell carcinoma and pancreatic cancer, and may be a potential prognostic factor. |
Application Dilution |
WB |
1:300-5000 |
IF(ICC) |
1:50-200 |