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DAXX Recombinant Monoclonal Antibody, Biotin Conjugated

Applications

  • WB
  • IHC-P
  • IHC-F

Reactivity

  • Human
Overview
Catalog # bsm-61231r-biotin-100ul
Product Name DAXX Recombinant Monoclonal Antibody, Biotin Conjugated
Applications WB, IHC-P, IHC-F
Reactivity Human
Specifications
Conjugation Biotin
Host Rabbit
Source KLH conjugated synthetic peptide derived from human DAXX
Clonality Monoclonal
Clone # Recombinant
Isotype IgG
Concentration Lot dependent
Purification Purified by Protein A.
Storage Buffer Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Storage Condition Store at -20°C for 12 months.
Target
Gene ID 1616
Swiss Prot Q9UER7
Subcellular location Cytoplasm, Nucleus
Synonyms Death domain-associated protein 6; Daxx; hDaxx; Fas death domain-associated protein; ETS1-associated protein 1; EAP1; DAXX; BING2; DAP6.
Background Transcription corepressor known to repress transcriptional potential of several sumoylated transcription factors. Down-regulates basal and activated transcription. Its transcription repressor activity is modulated by recruiting it to subnuclear compartments like the nucleolus or PML/POD/ND10 nuclear bodies through interactions with MCSR1 and PML, respectively. Seems to regulate transcription in PML/POD/ND10 nuclear bodies together with PML and may influence TNFRSF6-dependent apoptosis thereby.
Application Dilution
WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500