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DAXX Recombinant Antibody

Applications

  • WB
  • FCM
  • IHC-P
  • IHC-F
  • IF(ICC)
  • IF

Reactivity

  • Human
Overview
Catalog # bsm-61231r-100ul
Product Name DAXX Recombinant Antibody
Applications WB, FCM, IHC-P, IHC-F, IF(ICC), IF
Reactivity Human
Specifications
Conjugation Unconjugated
Host Rabbit
Source KLH conjugated synthetic peptide derived from human DAXX
Clonality Recombinant
Isotype IgG
Concentration Lot dependent
Purification Purified by Protein A.
Storage Buffer 10mM phosphate buffered saline(pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% sodium azide and 50% glycerol.
Storage Condition Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
Target
Gene ID 1616
Swiss Prot Q9UER7
Subcellular location Cytoplasm, Nucleus
Synonyms Death domain-associated protein 6; Daxx; hDaxx; Fas death domain-associated protein; ETS1-associated protein 1; EAP1; DAXX; BING2; DAP6.
Background Transcription corepressor known to repress transcriptional potential of several sumoylated transcription factors. Down-regulates basal and activated transcription. Its transcription repressor activity is modulated by recruiting it to subnuclear compartments like the nucleolus or PML/POD/ND10 nuclear bodies through interactions with MCSR1 and PML, respectively. Seems to regulate transcription in PML/POD/ND10 nuclear bodies together with PML and may influence TNFRSF6-dependent apoptosis thereby.
Application Dilution
WB 1:300-5000
FCM 1:20-100
IHC-P 1:200-400
IHC-F 1:100-500
IF(ICC) 1:50-200
IF